What is your opinion? Every NPC in Caladon try to kill me now. Even a members of thieves Underground.
That's why I like to keep a save before big world-changing slaughters. Kill the king on one path, let him live on the other. Depends on my character and the time of the month. For convenience, might want to save the assassination for when you're done with Caladon. Of course, some characters wouldn't care about such inconveniences.